Some Biological Properties of Human Chorionic Follicle Stimulating Hormone
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چکیده
منابع مشابه
Properties of follicle-stimulating hormone-receptor interactions. Specific binding of human follicle-stimulating hormone to rat testes.
Some properties of the interaction between radioiodinated human follicle stimulating hormone (lz51-hFSH) and its specific receptors in preparations of rat seminiferous tubule homogenate are described. Specific binding of lz51-hFSH by seminiferous tubule homogenate was appreciably greater than to Leydig cell homogenate of rat testes. The uptake of rz51-hFSH was hormone specific and uptake inhibi...
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A radioimmunoassay procedure for follicle-stimulating hormone in serum has been developed in which the assay mixture is incubated at 37#{176}C for a total of 22 h, rather than at 4#{176}C for 4-7 days. The withinassay coefficients of variation for the 37#{176}C and 4#{176}C methods, respectively, are 7.7% and 5.0%, while the between-assay variations are 13.8% and 9.9%. Comparison of values for ...
متن کاملFollicle-stimulating hormone and human spermatogenesis.
The role of follicle-stimulating hormone (FSH) in the control of spermatogenesis is not well established in any species, including man. We studied the effect of an experimentally-induced, selective FSH deficiency on sperm production in normal men. After a 3-mo control period, five normal men received testosterone enanthate (T) 200 mg i. m. weekly to suppress luteinizing hormone (LH) and FSH, un...
متن کاملSpecificity of cognate ligand-receptor interactions: fusion proteins of human chorionic gonadotropin and the heptahelical receptors for human luteinizing hormone, thyroid-stimulating hormone, and follicle-stimulating hormone.
The family of glycoprotein hormones and their homologous heptahelical receptors represent an excellent system for comparative structure-function studies. We have engineered single chain molecules of human chorionic gonadotropin (hCG) fused to its cognate receptor, LH receptor (LHR), and to the noncognate receptors, TSH receptor (TSHR) and FSH receptor (FSHR; N-beta-alpha-receptor-C), to create ...
متن کاملDissociation of human follicle-stimulating hormone. Comparison with luteinizing hormone.
Rat testis tissue receptor assays were utilized to study the kinetics of dissociation of human follicle-stimulating hormone (hFSH) and luteinizing hormone (hLH) under varying conditions of urea concentration and pH. In these competitive protein binding assays, 125I-hFSH and 125I-hLH were the radioligands and hormone dissociation was followed by a decrease in the ability of the dissociating horm...
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ژورنال
عنوان ژورنال: Endocrinologia Japonica
سال: 1975
ISSN: 0013-7219,2185-6370
DOI: 10.1507/endocrj1954.22.585